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Articles (41)
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[Current Topics in Microbiology and Immunology] RNA Interference Volume 320 || The Mechanism of RNase III Action: How Dicer Dices

Paddison, Patrick J., Vogt, Peter K.

Année:

2008

Langue:

english

Fichier:

PDF, 418 KB

english, 2008

Exit from Pluripotency Is Gated by Intracellular Redistribution of the bHLH Transcription Factor Tfe3

Betschinger, Joerg, Nichols, Jennifer, Dietmann, Sabine, Corrin, Philip D., Paddison, Patrick J., Smith, Austin

Journal:

Cell

Année:

2013

Langue:

english

Fichier:

PDF, 2.87 MB

english, 2013

[Current Topics in Microbiology and Immunology] RNA Interference Volume 320 || RNA-Mediated Transcriptional Gene Silencing in Human Cells

Paddison, Patrick J., Vogt, Peter K.

Année:

2008

Langue:

english

Fichier:

PDF, 209 KB

english, 2008

Comparison of glioblastoma (GBM) molecular classification methods

Lee, Eunjee, Yong, Raymund L., Paddison, Patrick, Zhu, Jun

Journal:

Seminars in Cancer Biology

Année:

2018

Langue:

english

Fichier:

PDF, 978 KB

english, 2018

Smarcc1/Baf155 Couples Self-Renewal Gene Repression with Changes in Chromatin Structure in Mouse Embryonic Stem Cells

Christoph Schaniel, Yen-Sin Ang, Kajan Ratnakumar, Catherine Cormier, Taneisha James, Emily Bernstein, Ihor R. Lemischka, Patrick J. Paddison

Journal:

STEM CELLS

Année:

2009

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2009

A resource for large-scale RNA-interference-based screens in mammals

Paddison, Patrick J., Silva, Jose M., Conklin, Douglas S., Schlabach, Mike, Li, Mamie, Aruleba, Shola, Balija, Vivekanand, O'Shaughnessy, Andy, Gnoj, Lidia, Scobie, Kim

Journal:

Nature

Année:

2004

Langue:

english

Fichier:

PDF, 367 KB

english, 2004

Synthetic shRNAs as potent RNAi triggers

Siolas, Despina, Lerner, Cara, Burchard, Julja, Ge, Wei, Linsley, Peter S, Paddison, Patrick J, Hannon, Gregory J, Cleary, Michele A

Journal:

Nature Biotechnology

Année:

2004

Langue:

english

Fichier:

PDF, 350 KB

english, 2004

An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo

Hernando, Eva, Paddison, Patrick J., Cordon-Cardo, Carlos, Hannon, Gregory J., Lowe, Scott W., Hemann, Michael T., Fridman, Jordan S., Zilfou, Jack T.

Journal:

Nature Genetics

Année:

2003

Langue:

english

Fichier:

PDF, 1.82 MB

english, 2003

Second-generation shRNA libraries covering the mouse and human genomes

Silva, Jose M, Li, Mamie Z, Chang, Ken, Ge, Wei, Golding, Michael C, Rickles, Richard J, Siolas, Despina, Hu, Guang, Paddison, Patrick J, Schlabach, Michael R, Sheth, Nihar, Bradshaw, Jeff, Burchard,

Journal:

Nature Genetics

Année:

2005

Langue:

english

Fichier:

PDF, 395 KB

english, 2005

Delivery of short hairpin RNAs—triggers of gene silencing—into mouse embryonic stem cells

Schaniel, Christoph, Li, Feng, Schafer, Xenia L, Moore, Troy, Lemischka, Ihor R, Paddison, Patrick J

Journal:

Nature Methods

Année:

2006

Langue:

english

Fichier:

PDF, 239 KB

english, 2006

Cloning of short hairpin RNAs for gene knockdown in mammalian cells

Paddison, Patrick J, Cleary, Michele, Silva, Jose Maria, Chang, Kenneth, Sheth, Nihar, Sachidanandam, Ravi, Hannon, Gregory J

Journal:

Nature Methods

Année:

2004

Langue:

english

Fichier:

PDF, 159 KB

english, 2004

Production of complex nucleic acid libraries using highly parallel in situ oligonucleotide synthesis

Cleary, Michele A, Kilian, Kristopher, Wang, Yanqun, Bradshaw, Jeff, Cavet, Guy, Ge, Wei, Kulkarni, Amit, Paddison, Patrick J, Chang, Kenneth, Sheth, Nihar

Journal:

Nature Methods

Année:

2004

Langue:

english

Fichier:

PDF, 424 KB

english, 2004

RNA interference: the new somatic cell genetics?

Patrick J Paddison, Gregory J Hannon

Journal:

Cancer Cell

Année:

2002

Langue:

english

Fichier:

PDF, 270 KB

english, 2002

[Current Topics in Microbiology and Immunology] RNA Interference Volume 320 || RNAi Pathway in C. elegans: The Argonautes and Collaborators

Paddison, Patrick J., Vogt, Peter K.

Année:

2008

Langue:

english

Fichier:

PDF, 201 KB

english, 2008

[Current Topics in Microbiology and Immunology] RNA Interference Volume 320 ||

Paddison, Patrick J., Vogt, Peter K.

Année:

2008

Langue:

english

Fichier:

PDF, 2.26 MB

english, 2008

[Current Topics in Microbiology and Immunology] RNA Interference Volume 320 || A Role for RNAi in Heterochromatin Formation in Drosophila

Paddison, Patrick J., Vogt, Peter K.

Année:

2008

Langue:

english

Fichier:

PDF, 218 KB

english, 2008

BuGZ Is Required for Bub3 Stability, Bub1 Kinetochore Function, and Chromosome Alignment

Toledo, Chad M., Herman, Jacob A., Olsen, Jonathan B., Ding, Yu, Corrin, Philip, Girard, Emily J., Olson, James M., Emili, Andrew, DeLuca, Jennifer G., Paddison, Patrick J.

Journal:

Developmental Cell

Année:

2014

Langue:

english

Fichier:

PDF, 2.32 MB

english, 2014

Reviews of books

Freeman, T. W., Smith, J. S., Sugden, David, Stone, Jeffrey, Moffat, I., Jones, Huw, Chapman, Keith, Paddison, R., Henderson, J. W., Hart, Patrick, Kinniburgh, Ian, Dawson, Andrew, Thomson, N. R., Mor

Journal:

Scottish Geographical Journal

Année:

1987

Langue:

english

Fichier:

PDF, 657 KB

english, 1987

Integrative network analysis of signaling in human CD34 + hematopoietic progenitor cells by global phosphoproteomic profiling using TiO 2 enrichment combined with 2D LC-MS/MS and pathway mapping

Guo, Hongbo, Isserlin, Ruth, Chen, Xiaoji, Wang, Weijia, Phanse, Sadhna, Zandstra, Peter W., Paddison, Patrick J., Emili, Andrew

Journal:

PROTEOMICS

Année:

2013

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2013

P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis

Munekazu Yamakuchi, Craig D. Lotterman, Clare Bao, Ralph H. Hruban, Baktiar Karim, Joshua T. Mendell, David Huso, Charles J. Lowenstein and Patrick J. Paddison

Journal:

Proceedings of the National Academy of Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 1.71 MB

english, 2010

G9a/GLP-dependent H3K9me2 patterning alters chromatin structure at CpG islands in hematopoietic progenitors

Schones, Dustin E, Chen, Xiaoji, Trac, Candi, Setten, Ryan, Paddison, Patrick J

Journal:

Epigenetics & Chromatin

Année:

2014

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2014

CNS Anticancer Drug Discovery and Development Conference White Paper

Levin, Victor A., Tonge, Peter J., Gallo, James M., Birtwistle, Marc R., Dar, Arvin C., Iavarone, Antonio, Paddison, Patrick J., Heffron, Timothy P., Elmquist, William F., Lachowicz, Jean E., Johnson,

Journal:

Neuro-Oncology

Année:

2015

Langue:

english

Fichier:

PDF, 1.28 MB

english, 2015

Involvement of DDX6 gene in radio- and chemoresistance in glioblastoma

Cho, Yu, Kang, Wonyoung, Kim, Sung, Sa, Jason, Kim, Nayoung, Paddison, Patrick, Kim, Misuk, Joo, Kyeung, Hwang, Young-Il, Nam, Do-Hyun

Journal:

International Journal of Oncology

Année:

2016

Langue:

english

Fichier:

PDF, 997 KB

english, 2016

ATPS-60COMPREHENSIVE IDENTIFICATION OF GLIOBLASTOMA MULTIFORME THERAPEUTIC TARGETS AND GROWTH SUPPRESSOR GENES USING GENE EDITING

Toledo, Chad, Ding, Yu, Hoellerbauer, Pia, Davis, Ryan, Basom, Ryan, Girard, Emily, Corrin, Philip, Delrow, Jeffery, Clurman, Bruce, Olson, James, Paddison, Patrick

Journal:

Neuro-Oncology

Année:

2015

Langue:

english

Fichier:

PDF, 23 KB

english, 2015

RISK MANAGEMENT, INSURANCE AND HIGH TECHNOLOGY SMALL FIRMS

Deakins, David, Paddison, Andrew, Bentley, Patrick

Journal:

Journal of Small Business and Enterprise Development

Année:

1997

Langue:

english

Fichier:

PDF, 884 KB

english, 1997

Causal Mechanistic Regulatory Network for Glioblastoma Deciphered Using Systems Genetics Network Analysis

Plaisier, Christopher L., O’Brien, Sofie, Bernard, Brady, Reynolds, Sheila, Simon, Zac, Toledo, Chad M., Ding, Yu, Reiss, David J., Paddison, Patrick J., Baliga, Nitin S.

Journal:

Cell Systems

Année:

2016

Langue:

english

Fichier:

PDF, 7.34 MB

english, 2016

Screen for reactivation of MeCP2 on the inactive X chromosome identifies the BMP/TGF-β superfamily as a regulator of XIST expression

Sripathy, Smitha, Leko, Vid, Adrianse, Robin L., Loe, Taylor, Foss, Eric J., Dalrymple, Emily, Lao, Uyen, Gatbonton-Schwager, Tonibelle, Carter, Kelly T., Payer, Bernhard, Paddison, Patrick J., Grady,

Journal:

Proceedings of the National Academy of Sciences

Année:

2017

Langue:

english

Fichier:

PDF, 909 KB

english, 2017

Sensitivity to BUB1B inhibition defines an alternative classification of glioblastoma

Lee, Eunjee, Pain, Margaret, Wang, Huaien, Herman, Jacob A, Toledo, Chad M, DeLuca, Jennifer G, Yong, Raymund L, Paddison, Patrick, Zhu, Jun

Journal:

Cancer Research

Année:

2017

Langue:

english

Fichier:

PDF, 5.04 MB

english, 2017

Ion channel expression patterns in glioblastoma stem cells with functional and therapeutic implications for malignancy

Pollak, Julia, Rai, Karan G., Funk, Cory C., Arora, Sonali, Lee, Eunjee, Zhu, Jun, Price, Nathan D., Paddison, Patrick J., Ramirez, Jan-Marino, Rostomily, Robert C., Ulasov, Ilya

Journal:

PLoS ONE

Année:

2017

Langue:

english

Fichier:

PDF, 3.14 MB

english, 2017

GENE-12. EMERGING PRINCIPLES OF SYNTHETIC LETHALITY IN GLIOBLASTOMA

Hoellerbauer, Pia, Arora, Sonali, Feldman, Heather, Carter, Lucas, Girard, Emily J, Corrin, Philip, Olson, James M, Paddison, Patrick

Journal:

Neuro-Oncology

Année:

2017

Langue:

english

Fichier:

PDF, 92 KB

english, 2017

GENE-30. TRANSCRIPTION ELONGATION FACTORS REPRESENT IN VIVO CANCER DEPENDENCIES IN GLIOBLASTOMA

Miller, Tyler E, Liau, Brian, Wallace, Lisa C, Morton, Andrew, Xie, Qi, Dixit, Deobrat, Factor, Daniel, Kim, Leo, Morrow, James, Wu, Qiulian, Mack, Stephen, Hubert, Christopher, Paddison, Patrick J, H

Journal:

Neuro-Oncology

Année:

2017

Fichier:

PDF, 88 KB

2017

STEM-05. NEURAL G0: A NOVEL QUIESCENT-LIKE STATE IN PROLIFERATING HUMAN NEURAL STEM AND GLIOBLASTOMA TUMOR CELLS

Feldman, Heather, Arora, Sonali, Hoellerbauer, Pia, Pollard, Steven, Patel, Anoop, Plaisier, Christopher, Paddison, Patrick

Journal:

Neuro-Oncology

Année:

2019

Langue:

english

Fichier:

PDF, 87 KB

english, 2019

GENE-04. THE ONCOGENIC FUNCTIONS OF YAP1-GENE FUSIONS CAN BE INHIBITED BY DISRUPTION OF YAP1-TEAD INTERACTION

Szulzewsky, Frank, Hoellerbauer, Pia, Wu, Hua-Jun, Cimino, P J, Michor, Franziska, Paddison, Patrick, Vasioukhin, Valeri, Holland, Eric

Journal:

Neuro-Oncology

Année:

2019

Fichier:

PDF, 86 KB

2019

GENE-10. A SIMPLE AND EFFICIENT METHOD FOR GENERATING MULTI-ALLELIC INSERTION-DELETION MUTATIONS AND PRECISE DELETIONS IN PRIMARY HUMAN CELL CULTURES

Hoellerbauer, Pia, Kufeld, Megan, Arora, Sonali, Wu, Hua-Jun, Feldman, Heather, Paddison, Patrick

Journal:

Neuro-Oncology

Année:

2019

Fichier:

PDF, 87 KB

2019

A simple and highly efficient method for multiâallelic CRISPRâCas9 editing in primary cell cultures

Hoellerbauer, Pia, Kufeld, Megan, Arora, Sonali, Wu, HuaâJun, Feldman, Heather M., Paddison, Patrick J.

Journal:

Cancer Reports

Année:

2020

Fichier:

PDF, 2.40 MB

2020

BuGZ facilitates loading of spindle assembly checkpoint proteins to kinetochores in early mitosis

Shirnekhi, Hazheen K, Herman, Jacob A, Paddison, Patrick J, DeLuca, Jennifer G.

Journal:

Journal of Biological Chemistry

Année:

2020

Fichier:

PDF, 5.67 MB

2020

Efficient MultiâAllelic Genome Editing of Primary Cell Cultures via CRISPRâCas9 Ribonucleoprotein Nucleofection

Hoellerbauer, Pia, Kufeld, Megan, Paddison, Patrick J.

Journal:

Current Protocols in Stem Cell Biology

Année:

2020

Fichier:

PDF, 912 KB

2020

CBMT-42. A GENOME-WIDE CRISPR-Cas9 SCREEN FOR GENES REGULATING QUIESCENT-LIKE STATES IN GLIOBLASTOMA

Feldman, Heather, Mihalas, Anca, Plaisier, Christopher, Patel, Anoop, Paddison, Patrick

Journal:

Neuro-Oncology

Année:

2019

Fichier:

PDF, 88 KB

2019

COMP-04. MODELING PRECISION ONCOLOGY FOR GLIOBLASTOMA THROUGH INTEGRATION OF DESCRIPTIVE, FUNCTIONAL, AND NETWORK-BASED GENOMICS

Hoellerbauer, Pia, Kufeld, Megan, Arora, Sonali, Girard, Emily, Olson, James, Biery, Matthew, Chambwe, Nyasha, Paddison, Patrick

Journal:

Neuro-Oncology

Année:

2019

Fichier:

PDF, 120 KB

2019

CBMT-30. TARGETING NICOTINAMIDE ADENINE DINUCLEOTIDE BIOSYNTHESIS IN CNS TUMORS

Lindsay, Ken, Brenner, Charles, Hockenbery, David, Paddison, Patrick

Journal:

Neuro-Oncology

Année:

2019

Fichier:

PDF, 88 KB

2019

CBMT-38. THERAPEUTIC INHIBITION OF THE SPLICEOSOME IN GLIOBLASTOMA: CHANGES FORM MINOR TO MAJOR

Bonifert, Tobias, Arora, Sonali, Fitzgibbon, Matthew, Paddison, Patrick

Journal:

Neuro-Oncology

Année:

2019

Fichier:

PDF, 91 KB

2019